I prefer to listen to 5.1 sound reduced to two channel stereo. I find sound coming at me from all directions very disconcerting. It confuses my ageing ears.
With good speakers I don't need a centre channel when sitting directly in front of a telly in a relatively small space.
This observation, of course, is quite a separate issue from the acceptable use of a 5.1 AV amp in two channel stereo mode for playing music.
Those who do enjoy 5.1 sound can, I believe, with the proper choice of products use the same system for excellent two channel stereo.



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